The abnormal erythrocytes are sphereshaped spherocytosis rather than the normal biconcave disk shaped. The disorder is caused by mutations in genes relating to membrane proteins that allow for the erythrocytes to change shape. He showed in 1907 that the special theory of relativity of 1905, developed by his former student albert einstein, could be understood geometrically as a theory of fourdimensional spacetime, now known as the minkowski spacetime. Elle touche environ une personne sur 5 000, generalement dethnie blanche nordeuropeenne. The clinical, biological, and morphological aspects as well as the treatment of this morbid association were studied in three patients.
The normal range of red blood cell osmotic fragility and autohemolysis was determined in venous blood of 32 healthy newborn infants. Hereditary spherocytosis is an abnormality of red blood cells, or erythrocytes. One of the rst consistency results in the egative direction was proved by brendle and the rst author. Interet potentiel des images parametriques des temps d. Hermann minkowski 22 june 1864 12 january 1909 was a german mathematician and professor. Neonatal manifestations of hereditary spherocytosis. Dec 29, 2011 the classical minkowski problem has a natural extension to hedgehogs, that is to minkowski differences of closed convex hypersurfaces.
Pernicious anemia is a chronic illness caused by impaired absorption of vitamin b because of a lack of intrinsic factor if in gastric. Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders. Read occurrence and characteristics of hereditary spherocytosis in algeria, european journal of haematology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. These genes give the body instructions to make proteins that exist on the membranes of red blood cells. Neonatal manifestations of hereditary spherocytosis jama. Several abnormalities have beendescribed, suchasdisturbances in. These proteins carry molecules in and out of cells, keep cell structure, and attach to other proteins. Clinically, the disease manifests itself depending on the various mutations of genes that encode membrane proteins, their various functional consequences, and the mode of inheritance. Some increase the flexibility of cells so they can easily travel from larger blood vessels to. Hereditary spherocytosis diagnosis, surgical treatment. Links to pubmed are also available for selected references. Occurrence and characteristics of hereditary spherocytosis. In mathematical physics, minkowski space or minkowski spacetime is a combination of threedimensional euclidean space and time into a fourdimensional manifold where the spacetime interval between any two events is independent of the inertial frame of reference in which they are recorded.
Verhandlungen des kongresses fur innere medizin, 1900, 18. Classical minkowski problem variants hyperbolic surfaces results introduction 2. Hereditary spherocytosis known as minkowski chauffard disease is a heterogeneous group of diseases affecting the red blood cells 1. Get a printable copy pdf file of the complete article 1017k, or click on a page image below to browse page by page. Hs known as well as the minkowski chauffard disease is the most common inherited red cell membrane disorder with one case out of 20003000 individuals, and probably. Join facebook to connect with julia minkowski and others you may know. The minkowski content named after hermann minkowski, or the boundary measure, of a set is a basic concept that uses concepts from geometry and measure theory to generalize the notions of length of a smooth curve in the plane, and area of a smooth surface in space, to arbitrary measurable sets. Still chauffard syndrome minkowskichauffard syndrome see under minkowski still chauffard syndrome synonyms. This page was last edited on 7 february 2019, at 14. Foliations and times algebraic level geometry flat mghc a priori compactness properness of cauchy surfaces uniform convexity regularity of isometric embedding spaces standard facts causality theory lorentz geometry of submanifolds ftimes the minkowski problem in. The metric tensor of the minkowski spacetime used in special relativity. Theprimarycauseoftheminkowcontrols 9560 19 2 varioushemolytic 8560 4 anemias 122 minkowski chauf290205 5 fardsyndrome 405 ski chauffard syndrome, alsocalled inherited microspherocytosis, isstill unknown. Diagnosis of hereditary spherocytosis in newborn infants.
Spherocytose hereditaire laboratoire dhematologie cellulaire du. Hereditary spherocytosis, elliptocytosis, and other red. Minkowski metric article about minkowski metric by the free. Should be a quick merge, as there isnt much content on the minkowski chauffard syndrome article. Megaloblastosis describes a heterogeneous group of disorders that share common morphologic characteristics. The name hereditary spherocytosis should be retained however, since this is more descriptive and also is how the disease is most widely known. Full text full text is available as a scanned copy of the original print version. Uniqueness results for the minkowski problem extended to. All structured data from the file and property namespaces is available under the creative commons cc0 license. Chauffard syndrome the symptoms of still disease in one suffering from bovine or other nonhuman form of tuberculosis. In this sense, minkowskis notion still remains an inspiring source for the clinical and psychotherapeutic understanding of schizophrenic vulnerability.
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